Indurate 发表于 2025-3-23 12:35:31

Limits to Responsibility and Decision-MakingAs a result of the thalidomide tragedy, routine animal testing of new drugs was introduced. This chapter discusses the value of animal experiments. Another consequence was an intensification of the reporting of adverse drug reactions. A sample of such reports are presented and commented upon.

过时 发表于 2025-3-23 16:06:12

Ethics and Reproductive BiologyThis chapter discusses the main epidemiological techniques which are used in studies of drugs and pregnancy outcomes: population studies, case-control studies, cohort studies, nested case-control studies, and the sibling approach. The principles of each study type are presented and advantages and disadvantages are pointed out and exemplified.

过渡时期 发表于 2025-3-23 20:21:36

http://reply.papertrans.cn/29/2832/283182/283182_13.png

广告 发表于 2025-3-24 00:45:46

,The “Alert Clinician”,This chapter illustrates how some drugs with a teratogenic potential were identified from clinical observations: thalidomide, anticonvulsants, warfarin, drugs for thyrotoxicosis, retinoids, and mycophenolate mofetil. It also stresses the limitations in this way to identify teratological hazards.

软弱 发表于 2025-3-24 03:12:02

Animal Experiments and Adverse Drug Reaction Reports,As a result of the thalidomide tragedy, routine animal testing of new drugs was introduced. This chapter discusses the value of animal experiments. Another consequence was an intensification of the reporting of adverse drug reactions. A sample of such reports are presented and commented upon.

encomiast 发表于 2025-3-24 08:26:06

Some Epidemiological Principles,This chapter discusses the main epidemiological techniques which are used in studies of drugs and pregnancy outcomes: population studies, case-control studies, cohort studies, nested case-control studies, and the sibling approach. The principles of each study type are presented and advantages and disadvantages are pointed out and exemplified.

凶猛 发表于 2025-3-24 13:04:40

http://reply.papertrans.cn/29/2832/283182/283182_17.png

Picks-Disease 发表于 2025-3-24 17:23:55

http://reply.papertrans.cn/29/2832/283182/283182_18.png

包庇 发表于 2025-3-24 21:48:13

http://reply.papertrans.cn/29/2832/283182/283182_19.png

体贴 发表于 2025-3-25 01:27:33

Refusal of Psychiatric Treatmentological studies help to identify causality but are burdened with methodological problems which will be discussed in this book. This chapter also introduces the Swedish Medical Birth Register and defines odds and risk ratios.
页: 1 [2] 3 4 5 6
查看完整版本: Titlebook: Drugs During Pregnancy; Methodological Aspec Bengt Källén Book 2016 Springer International Publishing Switzerland 2016 Epidemiological meth