半导体
发表于 2025-3-28 17:21:47
Introduction to the Windows Phone SDK,such an integrative predictor, we present four different classification schemes, i.e., an FDA labeling data-based approach (DILIrank dataset), a clinical evidence-based approach (LiverTox dataset), literature-based approaches (Greene and Xu datasets), and a registry-based approach (Suzuki dataset).
projectile
发表于 2025-3-28 20:40:46
E. Sally Rogers,Kim L. MacDonald-Wilsons to disrupt a biological process. Whereas the concentration of a drug in the liver is highly dependent on its physicochemical properties as these influence many pharmacokinetic characteristics. However, despite the ability to assess compounds for their potential to cause DILI using in silico method
ANT
发表于 2025-3-29 01:47:37
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STIT
发表于 2025-3-29 06:14:20
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Interdict
发表于 2025-3-29 10:37:22
Anxiety Disorders and Work Performanceded to illustrate how the in vitro assays can help to derisk preclinical in vivo toxicity findings and to better predict clinical human liver toxicity outcomes. Opportunities in the DILI field are also discussed, in particular the need to use more relevant in vitro models to better mimic the in vivo
厌烦
发表于 2025-3-29 14:57:40
Service Integration in Supported Employmentave contributed significantly to mechanistic studies of DILI, and various underlying signaling pathways and signatures of DILI have been identified. In this chapter, we first introduce the major hepatic lines (e.g., HepG2, Huh7, HepaRG, Hep3B, BC2, THLE, and Fa2N-4 cells), including their origins, c
GET
发表于 2025-3-29 18:59:42
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爱花花儿愤怒
发表于 2025-3-29 22:31:53
Danica Damljanović,Kalina Bontchevall-derived hepatocyte-like cells (PSC-HLCs) are a developing model which show promise for hepatotoxicity testing. However, the current phenotype of PSC-HLCs is closer to a fetal hepatocyte than an adult hepatocyte. The methodologies for generating mature PSC-HLCs close to an idealized hepatotoxicity
amplitude
发表于 2025-3-30 00:02:01
Milan Stanković,Jelena Jovanovićfolds, and bioprinting enable precise control over the cellular microenvironment for enhancing and stabilizing hepatic functions in the presence of NPC types, including those derived from the liver towards determining their impact on DILI progression. The introduction of induced pluripotent stem cel
Detoxification
发表于 2025-3-30 07:42:01
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