Increment
发表于 2025-3-26 22:05:20
Markus Jelonek,Lukas Trost,Thomas Herrmannthe actin filament-binding protein drebrin and the microtubule-binding +TIP protein EB3. This pathway is regulated proximally by cyclin-dependent kinase 5 phosphorylation of drebrin but the upstream elements in the pathway have yet to be identified.
hypnotic
发表于 2025-3-27 02:53:14
Nikolaos Karagiannis,Debbie A. Mohammed regulated by a drebrin A-specific mechanism, is likely to affect the localization of drebrin E. In the adult brain, drebrin is mainly localized in dendritic spines, but in some nuclei, drebrin can be detected in neuronal somata as well as dendritic spines. The fact that the developmental changes in
JIBE
发表于 2025-3-27 07:30:34
Nikolaos Karagiannis,Debbie A. Mohammedic isoform, compensates for the genetic deletion of drebrin A. However, DAKO results in the loss of homeostatic plasticity of .-methyl-.-aspartate receptors (NMDARs). The NMDAR activation-dependent trafficking of the NR2A subunit-containing NMDARs from dendritic shafts into spine head cytoplasm is g
不妥协
发表于 2025-3-27 11:42:46
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隐语
发表于 2025-3-27 17:18:41
https://doi.org/10.1007/978-3-031-06592-7us via myosin II ATPase activation. The potentiated spines change to excited state because of the decrease in DF-actin and thus change their shape robustly. In LTP, the Ca. increase via NMDA receptors soon returns to the basal level, and α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor
Truculent
发表于 2025-3-27 19:26:10
Clinton Enoch,Christoph Krause,Jane Porathpresynaptic change in AD brains. In addition, dysregulation of glutamate receptor trafficking and the p21-activated kinase/LIM kinase pathway has been observed in AD brains. It is now believed that soluble Aβ oligomers, namely, Aβ-derived diffusible ligands (ADDLs), but not insoluble Aβ aggregation
注意
发表于 2025-3-27 22:51:41
Finland: Vocational Guidance in Finlandthology involved in neurodegeneration, Alzheimer’s disease (AD), other cognitive disorders, and aging..Bidirectional connexin channels are permeable to Ca. ions, IP3, ATP, and cAMP. Connexin hemichannels are important for paracrine regulation and can release and exchange energy with other cells usin
peak-flow
发表于 2025-3-28 02:43:48
https://doi.org/10.1007/978-3-031-06620-7 morphogenesis by cooperating with shank and activated Cdc42 small GTPase, suggesting a novel signaling pathway comprising Homer, drebrin, shank, and Cdc42 for spine morphogenesis. Drebrin sequesters spikar in the cytoplasm and stabilizes it in dendritic spines, leading to spine formation. Finally,
magnate
发表于 2025-3-28 07:57:35
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截断
发表于 2025-3-28 13:11:08
0065-2598 the non-nervous system. This work will appeal to researchers who are interested in cytoskeletal dynamics at membrane-cytoskeletal interface as well as the number of them who use drebrin as a tool, such as a mar978-4-431-56817-9978-4-431-56550-5Series ISSN 0065-2598 Series E-ISSN 2214-8019