FIR
发表于 2025-3-25 06:58:58
Book 2014s to pursue alternative model-based paradigms. The key question is: How to find innovative compounds and, subsequently, appropriate dosage regimens? .Written from the industry perspective and based on many years of experience, this book offers:.- Concepts for creation of drug-disease models, introdu
痛打
发表于 2025-3-25 10:50:02
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PAD416
发表于 2025-3-25 14:58:50
Population Analyses,the 1970s and have been continuously refined thereafter. Parameters can now be estimated using stochastic algorithms that avoid previous likelihood approximations. The search for covariates became automated and model diagnostic procedures much more extended, as exemplified by visual predictive checks.
GRACE
发表于 2025-3-25 19:10:47
upplementary material: .The development of innovative drugs is becoming more difficult while relying on empirical approaches. This inspired all major pharmaceutical companies to pursue alternative model-based paradigms. The key question is: How to find innovative compounds and, subsequently, appropr
NATTY
发表于 2025-3-25 20:41:53
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天文台
发表于 2025-3-26 02:21:01
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不透明性
发表于 2025-3-26 05:25:18
Berthold Heinrich,Wolfgang Schneidertreatment concept into a marketable drug, industry specialists increasingly advocate the consistent application of mathematical modeling based on realistic models of pharmacokinetics, pharmacodynamics, and disease biology.
Ornithologist
发表于 2025-3-26 10:07:02
Grundlagen der Motorprozessrechnungof a disease, disease progression models will mainly be built empirically. Drug-disease models help to identify and assess appropriate targets at an early state of drug development, as well as the planning of trials in later stages of development.
TRACE
发表于 2025-3-26 14:39:35
Background of Pharmacologic Modeling,treatment concept into a marketable drug, industry specialists increasingly advocate the consistent application of mathematical modeling based on realistic models of pharmacokinetics, pharmacodynamics, and disease biology.
数量
发表于 2025-3-26 19:51:55
Drug-Disease Modeling,of a disease, disease progression models will mainly be built empirically. Drug-disease models help to identify and assess appropriate targets at an early state of drug development, as well as the planning of trials in later stages of development.