CARK
发表于 2025-3-23 13:47:12
Hybridantriebe und Range Extenderthis purpose, the trial is simulated many times, taking into account fixed and random effects that were assessed in a previous population analysis. Also, the impact of ad hoc assumptions regarding the population to be treated, the dosage regimen including dosage adjustment rules, and the pharmacolog
parsimony
发表于 2025-3-23 16:56:12
Günter P. Merker,Christian Schwarzrgans (e.g., heart, liver, and brain), there are computational representations that have already proved their worth. The European Community financially supports activities in this area, such as the Drug Disease Model Resource (DDMoRe) as part of the Innovative Medicines Initiative (IMI) and the Huma
nullify
发表于 2025-3-23 18:45:27
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搜寻
发表于 2025-3-24 00:26:03
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言外之意
发表于 2025-3-24 03:28:41
Background of Pharmacologic Modeling,atients with differentiated medicines that can be afforded by health care systems is proving more and more difficult. Today’s medical treatment concepts are largely determined by drugs that act on predefined targets whereas previously a more phenomenological approach was taken. Drug development is a
HAVOC
发表于 2025-3-24 07:22:10
First Example of a Computational Model, on palmar and plantar skin. Models for tumor growth and skin turnover are combined with pharmacokinetic (PK) and pharmacodynamic (PD) models to assess the impact of two alternative dosing regimens on efficacy and safety. Both regimens deliver the same cumulative drug amount, but one regimen employs
Flawless
发表于 2025-3-24 11:09:13
Drug-Disease Modeling,treatments can be envisaged. Physiologic models of affected body organs or systems provide the basis for implementing disease mechanisms. The large amount of (patho)-physiologic information makes for potentially (over)elaborate physiologic/disease models. Drug-disease models combine pharmacologic mo
Intellectual
发表于 2025-3-24 15:38:15
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策略
发表于 2025-3-24 22:56:47
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Friction
发表于 2025-3-25 02:10:38
Outlook,rgans (e.g., heart, liver, and brain), there are computational representations that have already proved their worth. The European Community financially supports activities in this area, such as the Drug Disease Model Resource (DDMoRe) as part of the Innovative Medicines Initiative (IMI) and the Huma