硬化
发表于 2025-3-23 12:42:41
Introduction,y aspects of drug candidate selection in general to place into context the challenges that a drug discovery team would face for the selection of a dermal drug candidate. Finally, specific risks and opportunities for selecting such a dermal drug candidate are presented.
我要威胁
发表于 2025-3-23 16:50:23
Assessing Drug Concentration in Skin: Direct and Indirect Methods,teristics: very specific for a drug or disease, possibly impractical, possibly not quantitative, possibly lacking sensitivity or possibly at a too early stage of development. They cannot, therefore, be applicable as versatile techniques for studying topical pharmacokinetics.
纬线
发表于 2025-3-23 18:32:16
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细丝
发表于 2025-3-24 00:27:16
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FANG
发表于 2025-3-24 03:32:43
https://doi.org/10.1007/978-3-319-59504-7drug development; dermal pharmacokinetics; dermal drugs; dermal drug candidate selection; dermatology
indignant
发表于 2025-3-24 08:57:42
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esculent
发表于 2025-3-24 12:40:19
Lionel Trottet,Howard Maibach, MDThe only book of its kind that describes how the industry develops and selects dermal drugs, complete with its challenges and opportunities.Discusses how the science can be used for increased success
共同生活
发表于 2025-3-24 18:11:27
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揭穿真相
发表于 2025-3-24 19:53:15
Confucianism and SustainabilityHistorically most topical drug classes seem to have been originally developed following the pragmatic principle that, “if an existing drug with an interesting pharmacology is effective orally/systemically, and the target is in the skin, it could well work topically without giving side effects and, therefore, would deserve to be tried topically”.
放气
发表于 2025-3-24 23:28:17
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