duplicate
发表于 2025-3-26 23:57:50
Nucleoside Transport Into Cells,NT; SLC29 gene family) nucleoside transporters, which differ in their substrate selectivity and their energy requirements. Both nucleoside transporter families have also been involved in the transmembrane transport of nucleoside-derived compounds, many of them currently used in antiviral and antitum
退出可食用
发表于 2025-3-27 03:32:57
The Role of Deoxycytidine Kinase in DNA Synthesis and Nucleoside Analog Activation,nly enzyme that can supply cells with all four precursors of DNA; is capable of 5′-phosphorylation of the natural substrates deoxycytidine (dCyt), deoxyadenosine, and deoxyguanosine; and can be interconverted into thymine nucleotides. The deoxycytidine triphosphate (dCTP), in addition to DNA, can be
deficiency
发表于 2025-3-27 09:00:10
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思考才皱眉
发表于 2025-3-27 11:34:29
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档案
发表于 2025-3-27 16:54:29
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debble
发表于 2025-3-27 20:42:31
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不规则
发表于 2025-3-28 00:40:25
Clofarabine,the drug in acute leukemias is favorable relative to fludarabine or cladribine and may have prognostic value for its clinical activity. The toxicity profile of this agent is different from other nucleoside analogs in that it clearly has clinical activity when used as a single agent against adult acu
充满装饰
发表于 2025-3-28 02:19:44
,-Nucleosides as Chemotherapeutic Agents,des and nucleoside analogs are available. Among nucleoside analogs, nonnatural L-enantiomers have been particularly interesting. The most notable example is lamivudine, which has been playing an important role in the treatment of human immunodeficiency virus and hepatitis B virus infections. The rea
细菌等
发表于 2025-3-28 07:44:53
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Talkative
发表于 2025-3-28 13:13:08
,9-β-,-Arabinofuranosylguanine,1995 before a prodrug of ara-G, nelarabine, entered clinical trials. Ara-G is a deoxyguanosine analog that needs to be phosphorylated inside the cell for pharmacological activity. In the first and rate-limiting phosphorylation step, ara-G is a substrate of both the mitochondrial deoxyguanosine kinas