Bone-Scan
发表于 2025-3-26 21:23:05
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上坡
发表于 2025-3-27 01:23:17
https://doi.org/10.1007/978-3-319-66104-9because of their long successful track record, provide an element of comfort for treating physicians. Contained within this larger category are the epipodophyllotoxins (VP-16, or etoposide; and VM-26, or teniposide), anthracyclines (doxorubicin, or adriamycin; daunorubicin, or daunomycin; idarubicin
Terrace
发表于 2025-3-27 07:48:59
https://doi.org/10.1007/978-3-319-63519-4ng to irreversible DNA double-strand breaks and apoptosis. In addition, recent evidences demonstrated that camptothecins have specific transcription-dependent effects that are independent from DNA breaks at replication forks. Here, we focus on the latter drug effects, discussing the influence of Top
凝乳
发表于 2025-3-27 10:28:14
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saphenous-vein
发表于 2025-3-27 14:03:04
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Embolic-Stroke
发表于 2025-3-27 18:18:37
Artificial Intelligence and Green Computing). The main function of all topoisomerases is to dissipate the torsional stress (supercoiling of the DNA) generated during DNA transactions such as transcription, replication, chromosome condensation, and segregation (Castano et al. 1996; Champoux 2001; Leppard and Champoux 2005; Zhang et al. 1988,
defeatist
发表于 2025-3-27 22:33:26
Hamza Hamout,Abderrahmane Elyousfiagents, termed topoisomerase poisons generate protein-linked DNA strand that block transcription and replication, leading to cell death. Cells treated with topoisomerase targeting drugs rely on diverse repair pathways to maintain genome stability and cell survival. This chapter summarizes current in
船员
发表于 2025-3-28 06:08:07
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尖叫
发表于 2025-3-28 10:14:35
DNA Topoisomerases and Cancer978-1-4614-0323-4Series ISSN 2196-9906 Series E-ISSN 2196-9914
bronchiole
发表于 2025-3-28 11:16:36
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