替代品
发表于 2025-3-26 23:13:42
https://doi.org/10.1007/978-1-349-00952-7 binding and hydrolysis, helicases behave as molecular motors capable of efficiently disrupting the many noncovalent hydrogen bonds that stabilize DNA molecules with secondary structure. In addition to their importance in DNA damage sensing and signaling, DNA helicases facilitate specific steps in D
Stagger
发表于 2025-3-27 01:06:42
Creativity and Parkinson’s Disease was established by measuring the resistance capacity of .deficient mouse embryonic fibroblasts (MEFs) transfected with mammalian expression constructs. Here, we describe the methods used to assess colony survival following the treatment of transfected cells with genotoxic compounds. This approach p
Indolent
发表于 2025-3-27 08:29:49
https://doi.org/10.1007/978-3-031-14724-1getable proteins beyond kinases and traditional enzymes. Many of the proteins involved in the DDR and repair impart their activity by making specific contacts with DNA. These protein–nucleic acid interactions represent a tractable target for perturbation with small molecules. We describe a high thro
单独
发表于 2025-3-27 09:52:40
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finite
发表于 2025-3-27 16:44:55
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Affirm
发表于 2025-3-27 21:24:03
Lata Balakrishnan,Jason A. StewartIncludes cutting-edge methods and protocols.Provides step-by-step detail essential for reproducible results.Contains key notes and implementation advice from the experts
纵火
发表于 2025-3-27 22:57:25
Methods in Molecular Biologyhttp://image.papertrans.cn/d/image/260176.jpg
冷漠
发表于 2025-3-28 02:50:15
Attention Deficit Hyperactivity Disorder,hat ALT telomeres are subjected to chronic replication stress. Here, we will review the features of telomeric DNA that challenge the replication machinery and also how the cell overcomes these challenges to maintain telomere stability and ensure the faithful duplication of the human genome.
不如屎壳郎
发表于 2025-3-28 10:02:19
Scintillation and Apparent Motion, Together, we aim to provide robust visualization methods employing laser-microirradiation to detect and determine protein behavior, functions and dynamics in response to DNA damage in mammalian cells.
船员
发表于 2025-3-28 12:08:40
Shared Reflections and Dialoguesve information about dNTP pools in different genetic and environmental contexts in vivo. Here we describe a high-throughput fluorescence-based assay that uses a qPCR-based approach to quantify dNTP levels for use with . extracts.