deadlock 发表于 2025-3-25 05:16:20
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Fish Lectins in Host–Pathogen Interactioncreatic duct adenocarcinoma, urinary transitional cell carcinoma, and gynecologic carcinoma. At the protein level, intensity and intracellular localization of DJ-1 expression is varied, and the DJ-1 protein regulates cancer progression, clinical aggressiveness, differentiation, cancer cell morpholog笨拙处理 发表于 2025-3-25 16:24:55
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V. Ramasubramanian,V. Brindha Priyadarisinie at position 106 (C106) is crucial for determination of the activation level of DJ-1..DJ-1 binds to many proteins, including various transcription factors, and acts as a coactivator or corepressor for regulating their target genes without direct binding to DNA, thereby affecting various cell functiHEW 发表于 2025-3-26 01:00:35
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Joaquim I. Goes,Helga do R. Gomess been identified as a causative gene of a familial form of Parkinson’s disease, ., and plays a significant role in antioxidative defense, protecting cells from oxidative stress. A cysteine residue of DJ-1 at position 106 (Cys-106) is preferentially oxidized under oxidative stress. This reactive Cyscalorie 发表于 2025-3-26 13:45:41
Tatiana A. Rynearson,Susanne Menden-Deuereta cells that finally cause chronically elevated blood glucose concentrations. Here we review the role of ubiquitously expressed antioxidant protein DJ-1 in the pathogenesis of T2DM. In beta cells, DJ-1 protects against oxidative stress, endoplasmic reticulum stress, and streptozotocin- and cytokinCounteract 发表于 2025-3-26 18:39:41
Joaquim I. Goes,Helga do R. Gomese nigrostriatal pathway. Loss-of-function mutations in the gene encoding PARK7/DJ-1 were identified in familial PD. Wild-type DJ-1 acts as an oxidative stress sensor in neural cells. Previously, we identified binding compounds of DJ-1, including UCP0045037/compound A, UCP0054278/compound B, and comp