大包裹
发表于 2025-3-30 08:51:01
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Brain-Imaging
发表于 2025-3-30 15:41:31
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专横
发表于 2025-3-30 19:50:32
Bridget M. Ogilvie,Michele Jungeryls to confirm the diagnosis of CF in subjects with suggestive symptoms. Since these tests reflect CFTR function and thus relate to the basic disease process in CF, changes in these parameters are also being used to assess the pharmacologic effect of compounds aimed at restoring CFTR function. Howeve
毛细血管
发表于 2025-3-31 00:14:11
https://doi.org/10.1007/978-1-349-06136-5various pathological conditions including cystic fibrosis and secretory diarrhea. The identification of CFTR pharmacological modulators may be achieved by screening highly diverse synthetic or natural compound libraries using high-throughput methods. A convenient assay for CFTR function is based on
Decongestant
发表于 2025-3-31 01:26:02
Parasitic Protozoa in Macrophages in vitrof the protein and trafficking to the cell surface. Processing mutations appear to inhibit folding of CFTR so that it accumulates in the endoplasmic reticulum as a partially folded protein. Expressing the proteins in the presence of small molecules called correctors can repair CFTR folding defects. S
遗产
发表于 2025-3-31 09:00:45
B. Olivier,J. Mos,J. L. Slangencorrectors and potentiators on CFTR function and epithelial cell biology in the native pathological environment. Cultured HBE cells derived from CF patients exhibit many of the morphological and functional characteristics believed to be associated with CF airway disease in vivo, including abnormal i