酷热
发表于 2025-3-25 05:02:08
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mediocrity
发表于 2025-3-25 10:51:03
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LINE
发表于 2025-3-25 12:10:14
Analysis of CFTR Folding and Degradation in Transiently Transfected Cellsthe surface of the endoplasmic reticulum to select misfolded proteins for degradation. The folding status of F508del-CFTR is monitored by at least two ER quality control checkpoints. The ER-associated Derlin-1/RMA1 E3 complex appears to recognize folding defects in CFTR that involve misassembly of N
GLUE
发表于 2025-3-25 16:35:09
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BIBLE
发表于 2025-3-25 20:41:48
B. Olivier,J. Mos,J. L. Slangenhe development and validation of the CF HBE pharmacology model and its use to characterize, optimize, and select clinical candidates. It is expected that the pre-clinical testing of CFTR potentiators and correctors using epithelial cell cultures derived from CF patients will help to increase their likelihood of clinical efficacy.
灰姑娘
发表于 2025-3-26 00:42:12
Animal Models in Psychopharmacologyy available delivery method and established and novel outcome measures. We highlight the logistic and regulatory complexities of such a clinical programme and finally, we look to the future and consider possible alternative strategies.
ostrish
发表于 2025-3-26 04:31:43
https://doi.org/10.1007/978-3-031-46456-0f digested and ligated, crosslinked chromosomes to measure physical interactions between distal genomic regions. When used together, these methods provide a powerful avenue to discover transcriptional regulatory elements within large genomic regions.
良心
发表于 2025-3-26 12:19:59
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Immunization
发表于 2025-3-26 14:03:16
Use of Primary Cultures of Human Bronchial Epithelial Cells Isolated from Cystic Fibrosis Patients fhe development and validation of the CF HBE pharmacology model and its use to characterize, optimize, and select clinical candidates. It is expected that the pre-clinical testing of CFTR potentiators and correctors using epithelial cell cultures derived from CF patients will help to increase their likelihood of clinical efficacy.
Nebulous
发表于 2025-3-26 18:34:18
Design of Gene Therapy Trials in CF Patientsy available delivery method and established and novel outcome measures. We highlight the logistic and regulatory complexities of such a clinical programme and finally, we look to the future and consider possible alternative strategies.