微粒 发表于 2025-3-23 11:48:24
Sensors and Sensing: A Biologist’s View. Proteins that mediate silencing affect all of these nuclear processes. Similarly proteins involved in replication, repair, and chromosome structure play a role in the formation and maintenance of silenced heterochromatin. In this chapter we describe a handful of simple tools and methods that can b即席 发表于 2025-3-23 17:55:28
https://doi.org/10.1007/978-3-7091-6025-1s called cohesinopathies have been associated with genetic mutations in cohesin subunit genes or genes encoding regulators of cohesin function. Studies in different model systems, from yeast to mouse have provided insights into the molecular mechanisms of action of cohesin/cohesin regulators and the有节制 发表于 2025-3-23 20:58:49
Sensors and Sensing: An Engineer’s Viewand the organization of chromatin in interphase cells. To study cohesin’s role in gene expression and chromatin organization, it is necessary to avoid secondary effects due to disruption of vital cohesin functions in the cell cycle. Here we describe experimental approaches to achieve this and the me凝乳 发表于 2025-3-24 01:36:55
http://reply.papertrans.cn/23/2293/229233/229233_14.pnggrovel 发表于 2025-3-24 05:16:27
Ruzena Bajcsy,Eric Krotkov,Max Mintzn promotes homologous recombination (HR) repair of DNA double-strand breaks (DSBs), which is conserved from yeast to humans, and is a critical effector of ATM/ATR DDR kinase-mediated checkpoint control in mammalian cells. Optical laser microirradiation has been instrumental in revealing the damage sA简洁的 发表于 2025-3-24 07:46:49
Ruzena Bajcsy,Eric Krotkov,Max Mintzyotic genomes, little is known about the molecular basis of this chromosome condensation process. Here, we describe in detail the protocol for a quantitative chromosome condensation assay in fission yeast cells, which is based on precise time-resolved measurements of the distances between two fluoreEnthralling 发表于 2025-3-24 11:04:15
http://reply.papertrans.cn/23/2293/229233/229233_17.png固执点好 发表于 2025-3-24 16:18:27
http://reply.papertrans.cn/23/2293/229233/229233_18.png认识 发表于 2025-3-24 21:58:21
Methods in Molecular Biologyhttp://image.papertrans.cn/c/image/229233.jpgHILAR 发表于 2025-3-25 00:56:17
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