Constituent
发表于 2025-3-26 22:00:41
Animal Paradigms to Assess Cognition with Translation to Humansd incorporating non-rodent species (e.g., non-human primates) that may enable a closer comparison to humans, an improvement in the translatability of the results will be possible. This chapter focuses on some promising translational cognitive paradigms for use in rodents, non-human primates, and hum
煞费苦心
发表于 2025-3-27 01:28:27
Signaling Pathways Relevant to Cognition-Enhancing Drug Targetss receptors, downstream signaling effectors , associated immediate early gene (e.g.
延期
发表于 2025-3-27 07:43:37
Role of Adult Hippocampal Neurogenesis in Cognition in Physiology and Disease: Pharmacological Targeion, recent genetic approaches have shown that promoting neurogenesis can positively modulate cognition associated with both physiology and disease. Thus the discovery of signaling pathways that enhance adult neurogenesis may lead to therapeutic strategies for improving memory loss due to aging or d
裂缝
发表于 2025-3-27 13:03:14
Attentionts for disorders of attention. These paradigms include two tasks of sustained attention that were developed as rodent analogues of the human Continuous Performance Task (CPT), the Five-Choice Serial Reaction Time Task (5-CSRTT) and the more recently introduced Five-Choice Continuous Performance Task
广大
发表于 2025-3-27 16:45:36
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搜寻
发表于 2025-3-27 18:15:23
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Offset
发表于 2025-3-27 22:35:27
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Ige326
发表于 2025-3-28 02:14:15
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uveitis
发表于 2025-3-28 07:34:02
Methods for Delivering and Evaluating the Efficacy of Cognitive Enhancementcan be facilitated through either pharmacological or remediation strategies. The critical goals of cognitive enhancement are to improve everyday functioning in multiple domains. This chapter describes the strategies that are most desirable for the treatment of cognitive impairments and detection of
Sad570
发表于 2025-3-28 14:04:11
Animal Paradigms to Assess Cognition with Translation to Humanst others. Impairments in cognition are prevalent in many neuropsychiatric and neurological disorders with few viable treatment options. The development of new therapies is challenging, and poor efficacy in clinical development continues to be one of the most consistent reasons compounds fail to adva