Allege
发表于 2025-3-28 17:41:05
http://reply.papertrans.cn/23/2262/226164/226164_41.png
休战
发表于 2025-3-28 22:36:01
https://doi.org/10.1007/978-3-642-99764-8 of functions include the regulation of cell growth, gene regulation, metabolic signaling, cell migration, and cell death. In this chapter, we detail how another of the lysosome’s crucial roles, cholesterol transport, plays a vital role in the control of ion channel function and neuronal excitabilit
opprobrious
发表于 2025-3-29 00:30:02
http://reply.papertrans.cn/23/2262/226164/226164_43.png
Engaging
发表于 2025-3-29 05:58:44
Anne Schurbohm-Ebneth,Hans Liecke channels are polymodal and are activated by several stimuli. Among TRPs, some members of this family of channels respond to changes in ambient temperature and are known as thermoTRPs. These proteins respond to heat or cold in the noxious range and some of them to temperatures considered innocuous,
不透明
发表于 2025-3-29 10:21:02
https://doi.org/10.1007/978-3-322-96478-6, fluid and electrolyte secretion, pain sensation, sensory transduction, and neuronal and muscle excitability. Their gating depends on the voltage-dependent binding of two intracellular calcium ions to a high-affinity site formed by acidic residues from α-helices 6–8 in each monomer. Phosphatidylino
粗鲁性质
发表于 2025-3-29 12:48:58
,Eigenkapitalveränderungsrechnung,gulatory mechanisms in the entire organism. One process mediating calcium signaling involves hydrolysis of phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P.) by the phospholipase-C (PLC). Thus, calcium and PtdIns(4,5)P. are intimately intertwined two second-messenger cascades that often depend on
弄污
发表于 2025-3-29 16:53:57
https://doi.org/10.1007/978-3-322-91148-3brane proteins. Chol is synthesized in the ER, but it is selectively enriched within the plasma membrane (PM) and other endomembranes, which requires Chol to cross the aqueous phase of the cytoplasm. In addition to the classical vesicular trafficking pathways that are known to facilitate the bulk tr
厨师
发表于 2025-3-29 21:17:27
http://reply.papertrans.cn/23/2262/226164/226164_48.png
摇晃
发表于 2025-3-30 02:51:49
https://doi.org/10.1007/9978-3-8349-9433-2racellular medium. To circumvent the hydrophobic barrier formed by the acyl chains of the lipid bilayer, protein channels and transporters are key players in the exchange of small hydrophilic compounds such as ions or nutrients, but they hardly account for the transport of larger biological molecule
Blasphemy
发表于 2025-3-30 05:29:36
https://doi.org/10.1007/9978-3-8349-9433-2ynthesized in the endoplasmic reticulum (ER) and require delivery to other organelles. In this scenario, formation of membrane contact sites (MCS) between neighbouring organelles has emerged as a novel non-vesicular lipid transport mechanism. Dissecting the molecular composition of MCS identified ph