奴才 发表于 2025-3-28 17:01:30
Biological Implications of the Niemann-Pick C Mutation,fic molecular mechanisms. The relative paucity of experimental techniques available to study intracellular lipid trafficking has made the delineation of inherited metabolic defects particularly critical for delineating metabolic pathways of transport.独轮车 发表于 2025-3-28 20:14:57
http://reply.papertrans.cn/23/2262/226154/226154_42.pngProgesterone 发表于 2025-3-29 02:26:54
Signaling Molecules Derived from the Cholesterol Biosynthetic Pathway,.., 1986; Porter and Spurgeon, 1981). These early studies led to the realization that the cyclic cholesterol molecule was derived from a polyisoprenoid, which in turn was shown to be composed of repeating five-carbon branched-chain building blocks derived from isopentenyl diphosphate (Rilling, 1985)去世 发表于 2025-3-29 06:39:26
,Coordinate Regulation of Cholesterol 7α-Hydroxylase and HMG-CoA Reductase in the Liver,HMGR), acyl cholesterol acyltransferase, cholesterol 7α-hydroxylase, and the LDL receptor (for a review, see Goldstein and Brown, 1990). The regulation of all these proteins is steroid dependent. This steroid-dependent regulation has been characterized in some detail at the gene level for HMG CoA syMultiple 发表于 2025-3-29 11:02:25
Polyprenyl Diphosphate Synthases,standing of the process of cholesterol biosynthesis. The discovery of isopentenyl diphosphate (IPP), made independently by Lynen ..(1958) and Bloch ..(1959), opened the era of enzymatic studies on the fundamental chain elongation, which starts with the condensation between IPP and dimethylallyl diph小步走路 发表于 2025-3-29 14:18:12
Antifungal Sterol Biosynthesis Inhibitors,ed in 1146 ., titled “Antidotarium Niclai” (Grun, 1991). During the following millennium, there has been continued interest in drug discovery and application. However, only in the last fifty years have effective therapeutic agents for fungal disease been developed that exploit a fundamental differen生存环境 发表于 2025-3-29 18:38:44
http://reply.papertrans.cn/23/2262/226154/226154_47.png雪崩 发表于 2025-3-29 22:01:23
http://reply.papertrans.cn/23/2262/226154/226154_48.png有机体 发表于 2025-3-30 02:02:48
http://reply.papertrans.cn/23/2262/226154/226154_49.pngbiopsy 发表于 2025-3-30 04:57:47
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