Occupation
发表于 2025-3-27 00:12:14
http://reply.papertrans.cn/23/2244/224398/224398_31.png
NEXUS
发表于 2025-3-27 01:47:05
http://reply.papertrans.cn/23/2244/224398/224398_32.png
absolve
发表于 2025-3-27 07:53:23
Long-Range Dependence in Heartbeat Dynamicsand function of proteins and peptide design as well as bioconjugation. Furthermore, .-thiolated/selenolated amino acids are important motifs in native chemical ligation-dechalcogenation strategy for protein synthesis. However, a universal method to access enantiopure .-thiolated/selenolated amino ac
Hla461
发表于 2025-3-27 11:42:42
http://reply.papertrans.cn/23/2244/224398/224398_34.png
改变立场
发表于 2025-3-27 14:34:05
http://reply.papertrans.cn/23/2244/224398/224398_35.png
制定法律
发表于 2025-3-27 20:41:31
https://doi.org/10.1007/978-1-4302-0310-0urrently available C-terminus functionalization strategies, we established an approach based on a small molecule cyanylating reagent that chemically activates a cysteine in a recombinant protein at its N-side amide for undergoing nucleophilic acyl substitution with amines. We demonstrated the versat
angiography
发表于 2025-3-28 01:14:57
Computer Graphics, the Fun, Easy Waya series of methods including CIH, TD coupling, Met-Met, and Cys-Met bis-alkylation strategy to switch peptides’ secondary structure and enhance their stability and cellular uptake. Here we focus on the peptide macrocyclization method of Met-Met and Cys-Met bis-alkylation strategy to generate more s
antecedence
发表于 2025-3-28 04:10:18
Computer Graphics, the Fun, Easy Wayficiency and mild aqueous reaction conditions, these ligases have emerged as powerful biotechnological tools for protein manipulation in recent years. PALs are enzymes of the asparaginyl endopeptidase (AEP) superfamily but have predominant transpeptidase activity as opposed to typical AEPs which are
铁塔等
发表于 2025-3-28 10:15:15
Computer Graphics, the Fun, Easy Wayforms). The study of glycosylation is significantly impeded because of the heterogeneous nature of glycoproteins. To overcome this challenge, we developed and optimized a glycoform library-based strategy to investigate the role of protein glycosylation. In this strategy, chemical synthesis was used
recede
发表于 2025-3-28 14:07:41
https://doi.org/10.1007/978-1-4302-0310-0medium. SetCys does not interfere with the native chemical ligation reaction under mild reducing conditions, that is in the absence of tris(2-carboxyethyl)phosphine (TCEP). In contrast, subjecting SetCys to TCEP results in the spontaneous loss of its .-selenoethyl appendage and thus to its conversio