compel 发表于 2025-3-23 11:41:35
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O. G. Castro,A. M. Ferreira,C. Valecific perfusion rates.Under these conditions, titer increases significantly, approaching the range of fed-batch titers. However,as dilution rate is decreased, a limit is reached below which performance declines due to poor growthand viability, specific productivity, or product instability. To overcoFillet,Filet 发表于 2025-3-23 20:31:57
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Fedbatch Culture and Dynamic Nutrient Feeding,process engineering willlikely require a combination of current process engineering strategies along with a better understandingand control over cell physiology. Process development will likely to entail not only optimizing traditionalengineering parameters but also engineering cell lines with desirMonotonous 发表于 2025-3-24 14:45:09
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Towards Industrial Application of Quasi Real-Time Metabolic Flux Analysis for Mammalian Cell Culturlation of inhibitory metabolites such as lactate. Changes in glucose, lactate and glutamine uptake/productionrates had significant effects on the calculation of other fluxes in the network. Sensitivity analysis ofthese key metabolic fluxes highlighted the need for accurate and reliable real-time sen极微小 发表于 2025-3-24 23:01:37
,Engineering Cells for Cell Culture Bioprocessing – Physiological Fundamentals,ineering cells for a more robust process. The concept of physiological homeostasisas a key determinant and its implications on cell engineering is emphasized. Integrating thephysiological perspective with cell culture engineering will facilitate attainment of dream cellswith superlative characteristblight 发表于 2025-3-25 02:52:57
Cell Culture Engineering978-3-540-34007-2Series ISSN 0724-6145 Series E-ISSN 1616-8542