condemn
发表于 2025-3-28 15:52:32
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tinnitus
发表于 2025-3-28 20:16:49
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创新
发表于 2025-3-29 00:54:26
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colony
发表于 2025-3-29 05:18:51
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SLUMP
发表于 2025-3-29 09:32:07
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Accommodation
发表于 2025-3-29 13:26:41
Silencing Genes in the Heartre the inducers of RNAi, but cultured primary cardiomyocytes and heart are highly resistant to siRNA transfection. This can be overcome by delivery of small hairpin (sh)RNAs or artificial microRNA (amiRNAs) by cardiotropic adeno-associated virus (AAV) vectors. Here we describe as example of the sile
grounded
发表于 2025-3-29 19:04:22
Generation of Efficient miRNA Inhibitors Using Tough Decoy ConstructsNAs known as microRNAs (miRNAs), and this mechanism is utilized by organisms ranging from plants to humans. MiRNAs are important downregulators of gene expression and are seen to be dysregulated in disease development. Thus inhibition of aberrantly upregulated miRNAs as a therapeutic approach has be
无聊的人
发表于 2025-3-29 20:13:21
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挥舞
发表于 2025-3-30 02:18:27
Direct Cardiac Reprogramming as a Novel Therapeutic Strategy for Treatment of Myocardial Infarctionmmon and morbid disease that is usually caused by irreversible loss of functional cardiomyocytes (CMs). Recently, we and others showed that in a murine model of acute myocardial infarction, delivery of three transcription factors, Gata4, Mef2c, and Tbx5 converted endogenous cardiac fibroblasts into
Nibble
发表于 2025-3-30 05:13:26
Production and Characterization of Vectors Based on the Cardiotropic AAV Serotype 9temic or regional vector delivery. In this chapter, we describe the most widely used production and purification method of AAV9. This production approach does not depend on the use of a helpervirus but instead on transient transfection of HEK293T cells with a plasmid containing the recombinant AAV g