啮齿动物 发表于 2025-3-26 22:21:37
Imaging Cancer Angiogenesis and Metastasis in a Zebrafish Embryo Modelival and migration can be tested by simply adding the compound into the water of living embryos. Therefore the zebrafish model offers the opportunity to gain more knowledge on cancer angiogenesis and metastasis in vivo with the final aim of providing new translational insights into therapeutic approLUMEN 发表于 2025-3-27 05:03:41
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The Zebrafish Xenograft Platform: Evolution of a Novel Cancer Model and Preclinical Screening Toolmary patient material by virtue of the relatively low number of cells required for each embryo (between 50 and 300 cells), the absence of an adaptive immune system in the early zebrafish embryo, and the short experimental timeframe (5–7 days). Following xenotransplantation into the fish, cells can bCRUDE 发表于 2025-3-27 11:33:29
Automation of Technology for Cancer Researchling and sorting, microfluidic systems for imaging and drug treatment, and image acquisition and analysis. Examples will be given of employment of these technologies within the fields of toxicology research and cancer research.LITHE 发表于 2025-3-27 16:41:30
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Selected Applications of Geostatical Methodspressors at the spatial and temporal level. Methods such as the Gal4/UAS or the Cre/lox systems paved the way to the development of elegant tumor models, which are now being used to study cancer cell biology, clonal evolution, identification of cancer stem cells and anti-cancer drug screening. CombiFLAT 发表于 2025-3-28 06:26:11
Selected Applications of Geostatical Methods. Zebrafish is a powerful model for studying tumorigenesis and has been successfully exploited in drug discovery. According to the zebrafish reference genome, 82 % of disease-associated genes in the Online Mendelian Inheritance in Man (OMIM) database have clear zebrafish orthologues. Using a variety使长胖 发表于 2025-3-28 11:49:18
Introducing Geostatistical Methods and tumors develop late in life. Functional inactivation of tumor suppressors is a crucial step in cancer progression and more and more tumor suppressor genes are being studied in zebrafish. Most often tumor suppressors have been inactivated by reverse genetics approaches using targeted disruption.