micronized
发表于 2025-3-25 06:00:32
Probing Calcium Channels with Venom Toxinscted to electrolysis.. The similarity of this inhibition to that produced by radiation and alkylating agents ultimately led to the discovery of the active antineoplastic agent cis-dichloro-diammine platinum II (cisplatin, DDP)..
Foreshadow
发表于 2025-3-25 10:58:01
Thomas L. Schwarz,Andrea J. Yool a .-hydroxyl group at the 2′-position ofthe sugar moiety. Because ara-C cytotoxicity is S-phase specific and correlates with the rate of DNA synthesis,. clinical use of the drug has been restricted to treatment of rapidly dividing tumors such as the leukemias. Recent interest has focused on ara-C a
贿赂
发表于 2025-3-25 14:14:14
Rainer Ortmann,Andreas Hein,Stefan Frentzelhe mechanism of action of these drugs has been extensively reviewed elsewhere.. These drugs have a very high affinity for tubulin and inhibit its polymerization. This leads to mitotic arrest and subsequent cell death. The vinca alkaloids are most active against premitotic cells and thus are cell cyc
嘲弄
发表于 2025-3-25 18:36:57
https://doi.org/10.1007/978-981-13-1370-7umor activity and its lack of myelosuppression.. Although its mechanisms of action may be multiple, the major effect appears to be related to its high affinity binding to the basic protein subunit of microtubules, tubulin, which results in disruption of the mitotic spindle apparatus and arrest of ce
URN
发表于 2025-3-25 22:21:38
Aluminum-Induced Neural Cell Death,ors, most notably testicular cancer, lymphomas, and squamous cell carcinoma of the head and neck. Its lack of myelotoxicity led to its early use in combination chemotherapy programs. The primary dose-limiting toxicity of bleomycin is pulmonary fibrosis.
角斗士
发表于 2025-3-26 00:34:51
Aluminum-Induced Neural Cell Death,rly established. This is particularly true of .-16. Although both drugs possess comparable in vitro activities in human tumors,. the use of .-26 has been somewhat limited to the treatment of childhood malignancies, and .-16 has been primarily tested in adults. .-16 has gained wide acceptance for the
Calibrate
发表于 2025-3-26 04:40:19
Aluminum-Induced Neural Cell Death, the alkylating group is such that the plasma half-life and therefore tumor exposure time is relatively short. The hesitancy for performing infusion trials with alkylating agents has been related to the misconception that such agents are more effective in noncycling, or G. cells. In fact, alkylating
CLOT
发表于 2025-3-26 12:23:02
Introduction to the Concept and Practice of Infusion Chemotherapyctions, arthritis, cardiovascular illness, to name but a few, are all managed by achieving optimal therapeutic drug levels and maintaining such levels continuously over time to ensure control of the disease process.
善于
发表于 2025-3-26 14:13:48
http://reply.papertrans.cn/23/2211/221075/221075_29.png
cardiopulmonary
发表于 2025-3-26 17:35:47
http://reply.papertrans.cn/23/2211/221075/221075_30.png