镇痛剂 发表于 2025-3-27 00:50:11
C-Myc in B-Cell Neoplasia978-3-642-60801-8Series ISSN 0070-217X Series E-ISSN 2196-9965Lucubrate 发表于 2025-3-27 04:56:04
https://doi.org/10.1007/978-3-642-60801-8DNA; apoptosis; cell; cytokine; growth; immunoglobulin; interferon; lymphoma; pathogenesis; protein; proteins;COLON 发表于 2025-3-27 06:28:31
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Current Topics in Microbiology and Immunologyhttp://image.papertrans.cn/c/image/220083.jpgSpartan 发表于 2025-3-27 13:48:10
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B-lymphocyte-lineage Cells from Early Precursors to Ig-secreting Plasma Cells: Targets of Regulationccurs as a consequence of chromosomal translocations to the IgH- and L-chain J segments which are frequently found in human Burkitt’s lymphomas, or to the IgH switch regions which are detected in mineral oil-induced mouse plasmacytomas . This signifies thnonplus 发表于 2025-3-28 00:56:52
Differential Regulation of the c-MYC P1 and P2 Promoters in the Absence of Functional Tumor Suppressw levels in normal proliferating cells . Minor fluctuations in MYC protein and/or mRNA levels can have dramatic outcomes on cellular physiology. Consequently, mammalian MYC gene expression is subject to tight control at multiple levels.激怒 发表于 2025-3-28 03:53:42
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Murine and Human 3′ IgH Regulatory Sequencestory elements but also the acquisition of different regulatory influences associated with its new, immunoglobulin-associated, chromosomal environment. The focus of this paper is on the nature of IgH associated sequences that impact upon the c-myc oncogene in B cell malignancies.CORD 发表于 2025-3-28 13:52:16
Role of c-myc and p27 in Anti-IgM Induced B-Lymphoma Apoptosiscause an increase in p27. Since dexamethasone causes a loss of myc and synergizes with the anti-IgM signal, we suggest that accelerated cell death with this steroid in the presence of anti-IgM is due to a more rapid degradation of this oncogene product. Finally, we propose that c-myc drives the tran