Morose
发表于 2025-3-25 04:11:39
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CARE
发表于 2025-3-25 09:12:06
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amnesia
发表于 2025-3-25 15:29:06
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anaerobic
发表于 2025-3-25 18:32:42
Microbial Extracellular Polymeric Substancesssion or inappropriate time of expression of the c-. gene has been found to promote apoptosis. Cleveland and coworkers observed that addition of a vector expressing c-Myc protein accelerated apoptosis following IL-3 deprivation of the 32D Independent myeloid cell line . Similarly Evan and coworke
sulcus
发表于 2025-3-25 23:38:58
Microbial Extracellular Polymeric Substanceso undetectable levels by 8–24 hours. These cells die soon thereafter via apoptosis. IgD receptor crosslinking also leads to an increase in c-myc expression, but it remains above baseline levels for more than 24 hours; these cells continue to proliferate and do not die. We previously reported that an
pester
发表于 2025-3-26 03:47:22
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Vulnerary
发表于 2025-3-26 08:11:08
https://doi.org/10.1007/978-1-4899-3121-4e to interact directly or indirectly with c-Myc and/or Max have been described (for review see Marcu et al. 1992; Henriksson and Lüscher 1996). It has become evident that at the center of this network lies Max which on one hand forms heterodimers with the Myc family of proteins, including c-, N-, an
讨厌
发表于 2025-3-26 10:40:37
Microbiological control of food production,he ability of c-Myc to transactivate through the E-box as the mechanism underlying all of these Myc functions. It is so widely accepted that c-Myc transactivation is necessary for cell transformation, that the authentication of putative target genes requires the presence of E-boxes within these gene
obstruct
发表于 2025-3-26 13:57:14
https://doi.org/10.1007/978-1-4614-1177-2f expression of a number of genes and this repressive effect of Myc on gene expression may not be mediated by the Myc/Max complex. We recently isolated by two-hybrid cloning a novel zinc-finger protein that associates with the carboxy-terminus of Myc. We have termed this protein Miz-1 (.yc-mteractin
裂隙
发表于 2025-3-26 17:16:45
P. Michael Davidson,Faith M. Critzerdimerize with Max through their respective helix loop helix (HLH) and leucine zipper (LZ) domains to cooperatively bind DNA in a sequence specific manner (reviewed in ). In contrast to the transactivating property of Myc/Max heterodimers , Max heterodimerization with Mad or Mxi1, foll