确认
发表于 2025-3-30 11:10:43
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保存
发表于 2025-3-30 14:07:34
The use of radiolabeled antibodies in bone marrow transplantation for hematologic malignancieselatively radiosensitive. Such preparative regimens have cured a substantial proportion of patients with both acute and chronic leukemia as well as lymphoma. However, despite the radiation sensitivity of hematologic malignancies, relapse remains a major cause of failure.
SPECT
发表于 2025-3-30 17:42:54
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受伤
发表于 2025-3-30 21:46:24
J. Brandmüller,R. Claus,L. Merten suggests that this is an important immunologic mechanism that contributes to the success of transplantation by eradicating residual disease. This phenomenon is referred to as the . (GVL) effect. Hence, as suggested by Mathe, allogeneic BMT can be considered a successful form of ‘adoptive immunotherapy’ .