ostracize
发表于 2025-4-1 05:06:55
Redox Regulation of Ap-1ells. Interestingly, Ref-1 is a bifunctional protein; it also possesses an apurinic/apyrimidinic (A/P) endonuclease DNA repair activity. However, the redox and DNA repair activities of Ref-1 are physically and biochemically distinguishable. Ref-1 may represent a novel component of the signal transdu
陶醉
发表于 2025-4-1 09:01:51
The Transcription Factor TCF/Elk-1PK Ser/Thr kinase activity by both oxidant and antioxidant stimuli, which temporally correlates with the appearance of hyperphosphorylated TCF/Elk-1. Thus antagonistic intracellular redox changes can lead to the same functional modulation of the nuclear transcription factor TCF/Elk-1 that was previo
oxidant
发表于 2025-4-1 10:41:08
Some Activities of the Oxidant Chromatethe nucleus, as only Cr(III) is detected bound to DNA. Thus it may be that only the Cr(III) formed . is toxic. Cr(VI) compounds are not mutagenic without metabolic reduction, (Petrilli and De Flora, 1978). The intermediates, Cr(V) and Cr(IV), are being investigated as putative toxins/carcinogens of
幼稚
发表于 2025-4-1 15:20:51
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誓言
发表于 2025-4-1 19:26:53
New Biological Reactive Intermediatesene oxides as electrophilic reactive metabolites. Much less was known until very recently about the metabolic oxidative activation of thiophene derivatives (Rance, 1989). A first report on the metabolism of thiophene itself in rats has shown the formation of thiophene-derived mercapturates in urine