Ballad
发表于 2025-3-25 05:21:14
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Longitude
发表于 2025-3-25 09:23:00
Psychoanalytische Heilerziehungte of its apparent disadvantages such as limited absorptive surface and moderate mucosal permeability, this route of administration might be of benefit especially for small- or medium-size peptide drugs. Potential advantages for intraoral delivery are the avoidance of gastrointestinal or liver first
浮雕宝石
发表于 2025-3-25 14:36:06
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CRAFT
发表于 2025-3-25 15:54:51
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phytochemicals
发表于 2025-3-25 20:12:29
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富饶
发表于 2025-3-26 03:07:17
https://doi.org/10.1007/978-3-658-16680-9he exchange of substances between blood and tissues is of prime importance. Capillary permeability to plasma proteins is a critical factor in regulating tissue-fluid balance. The endothelial cell monolayer lining the vessel wall is a porous (semipermeable) membrane through which fluid and solutes ar
Facet-Joints
发表于 2025-3-26 06:22:20
https://doi.org/10.1007/978-3-658-16680-9romolecule, transport of that molecule through the cell, and secretion or exocytosis of the molecule from the cell opposite the side of entry. The process has been described for a variety of molecules and a host of cell types; however, no cell type in which transcytosis has been proposed is more con
生气地
发表于 2025-3-26 11:04:39
https://doi.org/10.1007/978-3-531-92894-4or the elimination of most small proteins (Maack ., 1985; Rabkin and Kitaji, 1983). In health the glomerular capillary wall almost completely restricts the passage of molecules of molecular radius greater than ~ 42 Å (~ 50 kDa) while increasingly favoring the passage of proteins as their size decrea
留恋
发表于 2025-3-26 16:02:47
Karl Friedrich Bohler,Tobias Franzheld M.A.er, a protein therapeutic may also be seen as foreign. The result of being perceived as foreign can be benign, neutralize the activity of the therapeutic, or generate an adverse physiological response that may even be lethal. The protein may be intrinsically foreign because it has been obtained from
确定方向
发表于 2025-3-26 17:19:21
Protein Uptake and Cytoplasmic Access in Animal Cells ways of delivering drugs into cells—for instance, with the purpose of irreversibly inhibiting the protein synthesis machinery of cancer cells—mechanisms by which various protein ligands are internalized by cells and subsequently translocated across the membrane of intracellular compartments are coming into focus.