Radiation 发表于 2025-4-1 02:50:47

The Clinical Potential of NMR Imaging,sue and its matched normal (commonly blood or adjacent normal tissue) for side-by-side comparison. However, when interrogating entire genomes (or even just the coding regions), the number of sequencing errors easily outnumbers the number of real somatic mutations by orders of magnitudes. Here, we de

brachial-plexus 发表于 2025-4-1 07:03:41

The Clinical Potential of NMR Imaging,t of cancer and treatment therapies, the HLA locus plays a critical role in tumor recognition and tolerance mechanisms. In silico HLA class I and class II typing, as well as expression quantification from next-generation RNA sequencing, can therefore have great potential clinical applications. Howev

BLINK 发表于 2025-4-1 13:27:12

The Clinical Potential of NMR Imaging,le-molecule sequencing and ultralong reads. The technology is ideal for the typing of human leukocyte antigen (HLA) genes for transplantation and cancer immunotherapy. However, such applications have been hindered by the high error rate of nanopore sequencing reads. We developed the workflow and bio

假装是我 发表于 2025-4-1 16:16:55

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植物学 发表于 2025-4-1 21:31:59

https://doi.org/10.1007/978-3-642-69100-3r integration into high-throughput bioinformatic pipelines. Users can download models fit to publicly available data or train predictors on their own affinity measurements or mass spec datasets. This chapter gives a tutorial on essential MHCflurry functionality, including generating predictions, tra

欺骗世家 发表于 2025-4-2 02:39:03

https://doi.org/10.1007/978-3-642-93460-5neration sequencing (NGS) data is possible but requires the assembly of complex, multistep computational pipelines and extensive data preprocessing. Using public data from two cancer cell lines, here we show how TIminer, a framework to perform immunogenomics analyses, can be easily used to assemble

Alcove 发表于 2025-4-2 06:15:49

https://doi.org/10.1007/978-3-642-93460-5es. It is a Dockerized end-to-end pipeline that takes as input raw tumor/normal sequencing data. It is currently used in three clinical trials (NCT02721043, NCT03223103, and NCT03359239). In this chapter, we describe how to install and use OpenVax, as well as how to interpret the generated results.

ARY 发表于 2025-4-2 08:07:30

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查看完整版本: Titlebook: Bioinformatics for Cancer Immunotherapy; Methods and Protocol Sebastian Boegel Book 2020 Springer Science+Business Media, LLC, part of Spri