放气
发表于 2025-3-28 18:24:33
SomaticSeq: An Ensemble and Machine Learning Method to Detect Somatic Mutations,sue and its matched normal (commonly blood or adjacent normal tissue) for side-by-side comparison. However, when interrogating entire genomes (or even just the coding regions), the number of sequencing errors easily outnumbers the number of real somatic mutations by orders of magnitudes. Here, we de
对待
发表于 2025-3-28 19:58:58
HLA Typing from RNA Sequencing and Applications to Cancer,t of cancer and treatment therapies, the HLA locus plays a critical role in tumor recognition and tolerance mechanisms. In silico HLA class I and class II typing, as well as expression quantification from next-generation RNA sequencing, can therefore have great potential clinical applications. Howev
Arctic
发表于 2025-3-29 02:23:12
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Agnosia
发表于 2025-3-29 06:16:15
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阴郁
发表于 2025-3-29 08:36:54
High-Throughput MHC I Ligand Prediction Using MHCflurry,r integration into high-throughput bioinformatic pipelines. Users can download models fit to publicly available data or train predictors on their own affinity measurements or mass spec datasets. This chapter gives a tutorial on essential MHCflurry functionality, including generating predictions, tra
心神不宁
发表于 2025-3-29 11:48:49
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Budget
发表于 2025-3-29 17:10:44
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ineptitude
发表于 2025-3-29 19:45:44
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DRILL
发表于 2025-3-30 01:41:14
Identification of Epitope-Specific T Cells in T-Cell Receptor Repertoires,epitope-specific T cells has been instrumental in our understanding of cancer immunology and the development of personalized immunotherapies. To facilitate the study of T-cell epitope specificity, we developed a prediction tool, TCRex, that can identify epitope-specific T-cell receptors (TCRs) direc
光明正大
发表于 2025-3-30 04:05:50
Immunedeconv: An R Package for Unified Access to Computational Methods for Estimating Immune Cell Fesults of several methods. Given numerous dependencies and differences in input and output format of the various computational methods, comparative analyses can become quite complex. This motivated us to develop ., an R package providing uniform and user-friendly access to seven state-of-the-art com