辞职
发表于 2025-3-23 12:10:15
ered a broad range of eminent scholars and practitioners to provide a comprehensive review of modern bile acid research. The book offers clinical physicians, basic researchers and postgraduate students essential insights into cutting-edge research and paves the way for further research.978-4-431-56767-7978-4-431-56062-3
和平
发表于 2025-3-23 16:24:19
Metabolism of Bile Acids sulfate and glucuronide conjugates of bile acids also exist, which are hydrophilic and useful for urinary excretion. Bile acids with less hydroxyl groups are subjected to these conjugations, which are appropriate for the detoxication of toxic bile acids.
CLOWN
发表于 2025-3-23 18:25:14
Intestinal Digestion and Absorption except for the conjugated bile acids are finally taken up by the cells. Conjugation of bile acids with glycine or taurine maintains water solubility at an acidic pH and prevents nonionic passive absorption from the proximal small intestine, which allows bile acids to be absorbed efficiently by an a
affinity
发表于 2025-3-23 23:41:49
Nuclear Receptor Regulationese nuclear receptors regulate various physiological processes other than bile acid metabolism, such as glucose and lipid metabolism, cellular growth and differentiation, and immunity. Bile acid metabolism by intestinal microflora modulates nuclear receptor function in host cells. Bile acid-activate
昏暗
发表于 2025-3-24 05:40:36
Bile Acid as Therapeutic Agentsgs suggest that modulation of bile acid metabolism and/or signaling would be a potential therapeutic strategy for the treatment of several diseases. In this context, bile acid-related drugs (agents) such as ursodeoxycholic acid, bile acid mimetics, and bile acid sequestrants have garnered the attent
contradict
发表于 2025-3-24 09:46:49
Bile Acids and Cholestatic Liver Disease 1: Primary Biliary Cholangitis (PBC)t is targeted to cytotoxicity of hydrophobic bile acids; ursodeoxycholic acid (UDCA) exerts its effect through reduction of cytotoxicity of hydrophobic bile acids and stabilizing biliary HCO.. umbrella. Both bezafibrate and obeticholic acids are also capable of reducing cytotoxicity of hydrophobic b
类人猿
发表于 2025-3-24 10:43:13
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Immunotherapy
发表于 2025-3-24 15:11:43
Bile Acids and Cholestatic Liver Disease 3: Inborn Errors of Bile Acid Synthesisency, and bile acid-CoA ligase deficiency. Cholesterol 7α-hydroxylase deficiency and disorders of peroxisomal β-oxidation are not considered here, since cholesterol 7α-hydroxylase deficiency is not known to occur in children and disorders of peroxisomal β-oxidation represent disease of peroxisomes.
收集
发表于 2025-3-24 19:12:58
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宣称
发表于 2025-3-25 01:04:36
Bile Acids and Pancreatic Diseaseduced acinar cell injury. Pancreatic fluid secretion from ductal cells is influenced by the bile acids in a concentration-dependent manner, with a stimulatory effect at low concentrations and an inhibitory effect at high concentrations. It is expected to develop a specific medicine to prevent bile a