Uncultured
发表于 2025-3-23 13:16:01
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MUTE
发表于 2025-3-23 15:47:32
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coddle
发表于 2025-3-23 22:05:57
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intimate
发表于 2025-3-23 23:35:09
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残忍
发表于 2025-3-24 03:37:25
Institutional Development PerformanceRs). They are now also known to act as multifunctional adaptor proteins binding many non-receptor protein partners to control multiple signalling pathways. β-arrs therefore act as key regulatory hubs at the crossroads of external cell inputs and functional outputs in cellular processes ranging from
Progesterone
发表于 2025-3-24 07:01:40
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wreathe
发表于 2025-3-24 12:41:27
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Kernel
发表于 2025-3-24 16:11:26
Institutional Development Performanceegration of cellular signalling. We previously found that the angiotensin II (Ang II) type 1 receptor (AT1R) and the prostaglandin F2α (PGF2α) receptor (FP), both important in the control of smooth muscle contractility, form such a functional heterodimeric complex in HEK 293 and vascular smooth musc
标准
发表于 2025-3-24 21:54:00
Defining Institutional Development (ID) trafficking of internalized GPCRs to lysosomes. Ubiquitination of GPCRs is mediated by specific E3 ubiquitin ligases that are scaffolded by the adaptor proteins called β-arrestins. Traditionally, detection of GPCR ubiquitination is achieved by using ubiquitin antibodies to Western blot immunoprecip
AGOG
发表于 2025-3-25 01:59:33
https://doi.org/10.1007/978-981-13-7717-4proteins. Here we describe the methods used to identify the interaction sites of arrestin-binding partners on arrestin-3 and the use of monofunctional individual arrestin-3 elements in cells. Our in vitro pull-down assay with purified proteins demonstrates that relatively few elements in arrestin en