CHAR
发表于 2025-3-25 06:22:06
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constitute
发表于 2025-3-25 08:55:29
Simon McGrath,Martin Mulder,Rebecca Suart have a mammalian selection marker or do not have one suitable for all cell types, it is usually necessary to modify BAC clones to include a selection marker, a “retrofitting” process. Different BAC retrofitting strategies have been developed over the last 5 yr and are classified in the reference section (.–.).
morale
发表于 2025-3-25 12:30:20
https://doi.org/10.1007/978-3-319-14346-0ion of genetic markers broadened to include blood group and histocompatibility antigens, and protein allotypes. Around 1980, DNA itself became the marker (.), first with restriction fragment length polymorphisms (RFLPs) and then with amplification polymorphisms based on simple sequence lengths (SSLP
barium-study
发表于 2025-3-25 17:02:43
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使激动
发表于 2025-3-25 23:35:14
https://doi.org/10.1007/978-3-540-79567-4ize, which are free of methylation and these are known as CpG islands (. . . and . for reviews). In addition to distinctive DNA characteristics, CpG islands have an open chromatin structure in that they are hyperacetylated, lack histone H1, and have a nucleosome-free region (.). The major reason for
arboretum
发表于 2025-3-26 02:43:04
https://doi.org/10.1007/978-3-540-79567-4ridization (array CGH) provides a high throughput means to measure and map copy number aberrations on a genome-wide scale and to link them directly to genome sequence. For applications involving the analysis of tumors, the technology must provide reliable detection of single copy gains and losses in
condescend
发表于 2025-3-26 05:22:59
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STALL
发表于 2025-3-26 12:21:17
Simon McGrath,Martin Mulder,Rebecca Suart have a mammalian selection marker or do not have one suitable for all cell types, it is usually necessary to modify BAC clones to include a selection marker, a “retrofitting” process. Different BAC retrofitting strategies have been developed over the last 5 yr and are classified in the reference se
Cumbersome
发表于 2025-3-26 14:07:04
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exquisite
发表于 2025-3-26 18:28:57
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