澄清
发表于 2025-3-28 17:41:32
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CHURL
发表于 2025-3-28 21:38:43
Gregg D. Cappon,Donald G. Stump continually provided by either tonic or antigen-mediated BCR signals and other trophic factors. B-cell-activating factor (BAFF) has emerged as a key growth factor for B lymphocytes. Through its interaction with a TNF-R family member, BAFF-R or BR3, BAFF promotes survival of both immature and mature
委托
发表于 2025-3-28 23:37:24
https://doi.org/10.1007/978-981-99-1659-7tain self-tolerance, B cells that express antigen receptors with significant reactivity against self-antigens are prevented from receiving or responding to these survival signals. The great majority of B cells produced from bone marrow precursors fail to join the mature peripheral B-cell pool either
BOLT
发表于 2025-3-29 05:30:11
Mitsuharu Yoshiyama,Hidehiro Kakizakiinnate immune cells and stromal cells and are upregulated in response to various danger signals. By bindings to their receptors and signaling for the activation of NF-κB, they regulate multiple aspects of T cell-dependent and -independent antibody responses including B-cell survival, activation, cla
FICE
发表于 2025-3-29 08:34:39
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乐意
发表于 2025-3-29 15:22:17
Reference work 2023Latest editionportant regulator of immunity in both mice and humans. Although much has been learned about its signaling and physiological functions, its complexity in terms of ligand binding, cell-type-specific effects, as well as potential roles in human disease dictates that much work remains to be done in this
边缘带来墨水
发表于 2025-3-29 19:04:44
https://doi.org/10.1007/978-981-99-1659-7nce for understanding B-cell biology. Excessive BAFF production is associated with the development of autoimmune disorders such as lupus, a problem attributed to the inappropriate survival of self-reactive B cells. These early findings prompted the development of BAFF inhibitors, which are now in hu
BLINK
发表于 2025-3-29 23:21:45
Pharmacology of the Lower Urinary Tractcal features of systemic lupus erythematosus (SLE) and Sjögren’s syndrome (SS). Treatment with BLyS antagonists of mice with established SLE ameliorates disease progression and enhances survival. Moreover, similar treatment of mice with inflammatory arthritis ameliorates the ongoing inflammation and
讨好美人
发表于 2025-3-30 01:51:39
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Injunction
发表于 2025-3-30 08:01:52
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