mercenary 发表于 2025-3-28 14:56:39
Disruption of Axoplasmic Transport by Neurotoxic Agents. The 2,5-Hexanedione Modelch as colchicine and the vinca alkaloids (e.g. vincristine, vinblastine). These compounds, together with podophyllotoxin and the maytansinoids (maytansine and maytanprine), possess a special affinity for tubulin, block the formation of axonal microtubules and, perhaps for these reasons, disrupt axon死亡 发表于 2025-3-28 20:29:17
Axoplasmic Transport in the Experimental Neuropathy Induced by Acrylamidein these axonal enlargements (see review ). Pioneer investigations on axonal flow of labeled proteins have indicated that acrylamide intoxication interrupted slow axoplasmic transport in peripheral nerves, preferentially in sensory neurons . However, the impairment of slow axoplasmic flow waBRIDE 发表于 2025-3-29 00:35:00
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Disulfiram-Induced Impairment of Horseradish Peroxidase Retrograde Transport in Rat Sciatic Nerve axonal transport may play a role in the pathogenesis of peripheral neuropathies . We studied the relation between impaired axonal transport and nerve damage using the disulfiram neuropathy model of the rat . This animal model was developed as an experimental counterpart to the neuropathy obse刚开始 发表于 2025-3-29 08:02:40
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Axoplasmic Transport and Synaptic TransmissionThe aim of this contribution primarily is to give a short review of studies which point to the close dependence on anterograde axonal transport of events, related to synaptic transmission.STAT 发表于 2025-3-29 16:21:36
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https://doi.org/10.1057/9780230288614only been established for a short time. A trans-synaptic transfer of radioactive proteins at neuromuscular junctions was first suggested, but not clearly demonstrated, by the low resolution autoradiographs of Korr et al. in 1967 . In 1971 Bernice Grafstein demonstrated transfer of radioactivity