HIV763 发表于 2025-3-21 16:27:50
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Novel Infectious Diseases and Emerging Gram-Positive Multi-Resistant Pathogens in Hospital and Commulase-negative staphylococci), enterococci, streptococci, and . are the most important species of clinical interest. Antibiotic resistance issues are common among Gram-positive pathogens, especially among staphylococci and enterococci. Methicillin-resistant . (MRSA) and glycopeptide-resistant enterocCEDE 发表于 2025-3-22 03:49:28
Gram-Negative Pathogens: Overview of Novel and Emerging Resistant Pathogens and Drugsthe majority of untreatable bacterial infections. The variety of resistance and transfer mechanisms and their rapid spread among Gram-negative bacteria constitutes a global infection control challenge, and an urgent need for development of new antimicrobials. Unfortunately, infection rates with multreject 发表于 2025-3-22 05:13:31
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Daptomycin and Related Lipopeptides Produced by Fermentation, Chemical Modification, and Combinatoriomycin and related lipopeptides require Ca. for activity, and Ca.-bound daptomycin acts as a cationic peptide and interacts with the negatively charged phosphotidylglycerol (PG) in the cytoplasmic membrane to trigger its antibacterial effects. Mutants of ., ., . and ., which display incremental incrCERE 发表于 2025-3-22 18:12:37
Lantibiotics and Similar Peptides Produced by and Active on Gram-Positives: Discovery, Development aforming bridges that confer them characteristic structures. Most lantibiotics are antibacterials that bind to the cell wall precursor lipid II. They can be rod shaped or globular depending on the distribution of the lanthionine residues. Their biosynthetic pathway is relatively simple when comparedOsteoarthritis 发表于 2025-3-22 22:47:58
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Uridyl Peptide Antibiotics: Developments in Biosynthesis and Medicinal Chemistrydue. Included in this group are the pacidamycins, liposidomycins, capuramycins, and muraymycins. Most of these antibiotics are produced by . species and are naturally found as complexes of closely related congeners. The compounds all bear some resemblance to intermediates involved in cell wall biosycertitude 发表于 2025-3-23 06:25:56
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