正当理由
发表于 2025-3-21 16:40:44
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Exclaim
发表于 2025-3-21 23:43:59
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一再困扰
发表于 2025-3-22 03:30:54
Dihydrofolate Reductase Inhibitorsowerful, selective inhibition of the activity of malarial dihydrofolate reductase (. et al. 1969). Thus, one compound which was inadvertently synthesised as a prodrug and another which derived from a programme of synthesis of untargeted antimetabolites, together stand as prime examples of chemothera
瘙痒
发表于 2025-3-22 05:04:39
Lapinone, Menoctone, Hydroxyquinolinequinones and Similar Structures3-(9-hydroxy-9-pentyltetradecyl)1,4-naphthoquinone (II) (lapinone) was synthesised (. et al. 1948a) and shown to be effective in curing patients infected with . (. and . 1951). However, parenteral administration of the drug at fairly high doses was required and this, coupled with the emergence of su
Ataxia
发表于 2025-3-22 09:32:58
Antibioticsecies, chlortetracycline appeared to be somewhat more active than the other two compounds. The three drugs also exerted a causal prophylactic activity against sporozoite-induced infections of avian malaria. The two tetracyclines and chloramphenicol were the only antibiotics of those tested which wer
TERRA
发表于 2025-3-22 14:09:56
Book 1984 we asked the contributors to Part 2 of this volume to review very thoroughly the widely scattered but voluminous literature on those few chemical groups that have provided the antimalarial drugs in clinical use at the present time. Much can be learned from the history of their development and the p
Invertebrate
发表于 2025-3-22 20:15:57
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监禁
发表于 2025-3-22 22:38:19
Luis Baringo,Miguel Carrión,Ruth Domínguez abandoned (in favour of sontoquine) as being “too toxic for human use.” The magnitude of this error of judgement became apparent when, in the course of the American wartime antimalarial survey (. 1946), CQ proved to be the best of the many compounds which were tested for prophylactic-suppressive ac
encomiast
发表于 2025-3-23 03:18:27
Maedeh Yazdandoust,Masoud Aliakbar Golkarizontocide is more effective or less toxic than primaquine there is a recognised need for investigations to differentiate the efficacy and the toxicity of prima-quine as well as to discover new, less toxic, tissue schizontocides. Thus the Third Meeting of the Scientific Working Group on the Chemothe
Console
发表于 2025-3-23 07:46:41
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