多样 发表于 2025-3-26 23:28:11
http://reply.papertrans.cn/16/1585/158484/158484_31.pngexpdient 发表于 2025-3-27 04:18:40
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https://doi.org/10.1007/978-3-662-48505-7f a determined number of drugs to a determined site of the antibody, ensuring consistency between batches, minimizing the heterogeneity of the ADCs and making its properties more predictable. We focused on the commonly used site-directed conjugation strategies including engineered cysteine conjugatineutral-posture 发表于 2025-3-27 12:14:47
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http://image.papertrans.cn/a/image/158484.jpg返老还童 发表于 2025-3-28 02:35:17
https://doi.org/10.1007/978-981-19-5638-6Antibody-drug conjugates; Cellular Metabolic Dynamics; Cellular internalization; Intracellular traffick删除 发表于 2025-3-28 07:51:36
http://reply.papertrans.cn/16/1585/158484/158484_39.png爱哭 发表于 2025-3-28 10:35:16
Application of Antibody Fragments in ADCs,rized antibodies not only retain the specificity and affinity of total antibody, but also have faster tissue penetration and relatively short half-life, which can effectively avoid off-target toxicity. Therefore, the miniaturization of ADC is an effective method to solve the limitation of traditional ADC drugs.