Crater 发表于 2025-3-25 04:27:46
http://reply.papertrans.cn/16/1585/158484/158484_21.pngendoscopy 发表于 2025-3-25 11:05:50
http://reply.papertrans.cn/16/1585/158484/158484_22.png流利圆滑 发表于 2025-3-25 12:57:49
Antibody-Drug Conjugates and Cellular Metabolic DynamicsHeadstrong 发表于 2025-3-25 16:59:16
http://reply.papertrans.cn/16/1585/158484/158484_24.pngJunction 发表于 2025-3-26 00:04:11
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http://reply.papertrans.cn/16/1585/158484/158484_26.pngDetain 发表于 2025-3-26 07:53:32
Forschungsgruppe Konsum und Verhaltenother antibody derivatives all performed benign anti-tumor effects in clinical treatment, which make these therapies a promising future. However, these antibody-based agents all target tumor associated antigens (TAAs) while tumor specific antigens (TSAs), which brings drug resistance and adverse effCAND 发表于 2025-3-26 09:02:00
http://reply.papertrans.cn/16/1585/158484/158484_28.pnginspiration 发表于 2025-3-26 15:55:50
https://doi.org/10.1007/978-3-86226-389-9egradation and payload is released to target intracellular compartments to exert the anti-cancer effect. Considering that ADC takes effect intracellularly, the process of internalization and intracellular trafficking is thought to be crucial and need to be fully elucidated. Here, the internalization欢笑 发表于 2025-3-26 19:26:25
Mitbestimmungsrecht des Betriebsratesacy. During drug development, it is crucial for researchers to fully understand the metabolites and distribution of antibody-drug conjugates in circulation in human body, the data of which could be used to further optimize the drug design and to further improve the efficacy in clinical applications.