headlong
发表于 2025-3-23 13:38:55
Proximity (ProxiMol) and Step-Back Selectionsnically complex and this results in difficulties in specifically selecting antibodies which bind to a given cell surface molecule without selecting for a host of unwanted specificities in parallel. The desired antigen specificity can in many cases be obtained, but only after an intensive screening p
违抗
发表于 2025-3-23 15:38:39
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全能
发表于 2025-3-23 21:46:25
Selection of Human Antibody Fragments by Anti-Idiotypic Interaction compared to the background phages or the antigen is not available in a suitable form, resulting in nonspecific adherence of the phages. For this reason researchers used anti-idiotypic antibodies for the panning procedure. These were generated by immunization of rabbits with human IgG Fab (idiotype)
SPASM
发表于 2025-3-23 23:01:40
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金桌活画面
发表于 2025-3-24 06:07:50
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objection
发表于 2025-3-24 10:14:48
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erythema
发表于 2025-3-24 11:11:21
Recombinant Antibodiesle, an immense number of different molecules, bearing different specificities, is required. This diversity is generated by somatic recombination and hypermutagenesis of a set of variant genes. The genetic information for this repertoire of different antibodies is stored in the B-cell pool of our lymphatic system.
extinct
发表于 2025-3-24 18:33:22
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平淡而无味
发表于 2025-3-24 19:52:22
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遗产
发表于 2025-3-24 23:23:23
https://doi.org/10.1007/978-3-662-04605-0Amino acid; Antigen; Cell preparation; Expression; Immunologie; Polymerasekettenreaktion; Zellpreparatione