连锁 发表于 2025-3-28 15:16:25
Allgemeine Konstitutionspathologieniaturized experimental ASD screening methods, including solvent casting, solvent shift, coprecipitation, melt fusion, freeze drying, and spin coating. The criticality of understanding basic physicochemical properties of active pharmaceutical ingredient (API) in developing a successful ASD is discusEXALT 发表于 2025-3-28 19:02:53
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Allgemeine Konstitutionspathologie limits mobility and stabilizes amorphous drug; and (3) relative hydrophobicity, which limits plasticization of the SDD when stored at high relative humidity (RH) or in the presence of residual solvent from the spray-drying process..Spray drying has proven to be a robust and scalable method (from miradiograph 发表于 2025-3-29 04:29:48
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https://doi.org/10.1007/978-3-322-85317-2elopment approach helps to mitigate some risks associated with the MBP development, but the successful scale-up of process remains one of the most formidable challenges. From a simplistic approach, the MBP process can be considered as a solvent–antisolvent precipitation with rapid precipitation rateanatomical 发表于 2025-3-29 13:11:52
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Book 2014n the horizon, such as supercritical fluid processing, mesoporous silica, KinetiSol®, and the use of non-salt-forming organic acids and amino acids for the stabilization of amorphous systems..Amorphous Solid Dispersions: Theory and Practice .is a valuable reference to pharmaceutical scientists inter