GNAW
发表于 2025-3-23 12:45:28
http://reply.papertrans.cn/16/1548/154734/154734_11.png
NEG
发表于 2025-3-23 16:22:17
Theoretical Considerations in Developing Amorphous Solid Dispersionsn this book, the formulation scientist would benefit from a priori knowledge whether the amorphous route is a viable one for a given drug and how much solubility improvement, and hence increase in bioavailability, can be expected, and what forms of solid dispersion have been developed in the past. I
WAG
发表于 2025-3-23 18:36:12
http://reply.papertrans.cn/16/1548/154734/154734_13.png
BUCK
发表于 2025-3-24 01:39:50
Excipients for Amorphous Solid Dispersionsis chapter illustrates the challenges associated with amorphous solid dispersion stability and the role that excipients play in stabilization of amorphous solid dispersions by influencing the physicochemical properties of the drug molecule of interest. The classification of various excipients is cat
脆弱吧
发表于 2025-3-24 04:01:28
Miniaturized Screening Tools for Polymer and Process Evaluationompounds from pharmaceutical discovery in recent years. Although ASD has demonstrated drastic bioavailability enhancement, concerns over the physical instability remain as valid. By engineering amorphous solid dispersion with an appropriate polymer, the physical stability of ASD can be improved sign
Interferons
发表于 2025-3-24 08:22:58
http://reply.papertrans.cn/16/1548/154734/154734_16.png
保全
发表于 2025-3-24 12:01:04
HME for Solid Dispersions: Scale-Up and Late-Stage Developmentns. The proven scalability of the technology combined with the modular nature provides unmatched versatility. Extrusion has been utilized for dispersion manufacturing of commercial products across a range of scales and integrating with in-line monitoring technologies, it fully enables the benefits o
勤劳
发表于 2025-3-24 17:44:30
Spray Drying: Scale-Up and Manufacturingss characterization techniques. Special attention is given to the selection of right scale of spray dryer for any given processes and product demands, and also to the ancillary equipment. The main concerns and challenges involved in the establishment of an industrial process are discussed and exempl
DOTE
发表于 2025-3-24 22:54:54
http://reply.papertrans.cn/16/1548/154734/154734_19.png
清澈
发表于 2025-3-25 01:48:25
MBP Technology: Composition and Design Considerationsuch as particle size reduction, use of solubilizers, and complexing agents, in addition to lipid formulations, have been conventionally used but with limited success. When such approaches fail to provide desired bioavailability, amorphous formulations can be used as an alternate approach. However, a