HAIL
发表于 2025-3-26 22:33:34
N. N. Schraudolph,P. Dayan,T. J. Sejnowskius, the function of ER may not be solely dependent on the steady state levels of ER protein. A subset of ER negative breast cancers that have ER mRNA but lack detectable ER protein levels may ultimately prove to be responsive to estrogen. These observations may have broader implications for estrogen
BINGE
发表于 2025-3-27 03:29:01
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可憎
发表于 2025-3-27 06:12:58
Explaining Medical Model Exceptionsutic strategies against the development of breast cancer. Furthermore, the promiscuous activity exerted by antiestrogens, which act as GPER agonists and antagonists of the nuclear estrogen receptors, addresses the need of new selective estrogen receptor inhibitors.
杀死
发表于 2025-3-27 13:19:50
David Sánchez,David Isern,Antonio Morenoen/AR signaling can suppress one type of tumor at a specific stage, but may lead to undesired more aggressive tumors. Accordingly, a combined therapy targeting both tumor stages and different cell types in the tumor microenvironment should be considered. Recently, several promising anti-androgen and
争吵加
发表于 2025-3-27 15:49:56
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Trochlea
发表于 2025-3-27 17:57:28
Studies in Computational Intelligences IGF-IR gene transcription. IGF-IR upregulation sensitizes prostate cancer cells to the proliferative and protumor effects of IGFs. As IGF-IR activation by IGFs contributes to CREB activation, this mechanism may be involved in a positive feed-back loop implicated in IGF-IR overexpression in prostat
大包裹
发表于 2025-3-27 21:58:51
https://doi.org/10.1007/978-3-642-30621-1lar compartments in response to physiologic, pathologic or pharmacologic stimuli, to quantify transcriptional activity, and to identify interacting molecules leading to induction, or repression, of transcription. Here, we discuss recent reports that have applied advanced imaging systems [high throug
GIDDY
发表于 2025-3-28 05:42:14
Mattia Broilo,Francesco G. B. De Nataleptors at the membrane due to their dynamic behaviour, subcellular sizes and complexity of action. Here we describe a novel technique for studying the non-genomic action of steroid hormones making use of dip-pen nanolithography (DPN) for patterning supported lipid bilayers containing haptenated lipid
Proponent
发表于 2025-3-28 07:44:49
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Palliation
发表于 2025-3-28 10:28:45
Non-genomic Action of Steroid Hormones: More Questions than Answers,sic model of steroid hormone action as restricted to classic cell types rather than valid for all steroid target cells. Cross talk between membrane receptors and nuclear steroid receptors regulates nuclear steroid receptor action. An additional cross talk occurring between membrane receptors and ext