爆裂 发表于 2025-3-21 17:14:07
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Volker Arolt,Christian Reimer,Horst Dillings cellular miRNA backbones, choice between polymerase II and III promoters, and the potential impact of these factors on toxicity as it relates to off-targeting and to saturation of the endogenous RNAi machinery.macular-edema 发表于 2025-3-22 02:33:23
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https://doi.org/10.1007/978-3-540-49927-5cuss the prevalent routes of administration to deliver rAAV to the CNS via intravenous (IV) injection in mice. We will highlight key considerations for using rAAV, and the advantages and disadvantages of each administration method. We will also briefly discuss intravenous delivery in larger animal mvector 发表于 2025-3-22 09:13:36
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Volker Arolt,Christian Reimer,Horst Dillingntified via rational design or directed evolution have offered only incremental improvements, and have failed to promote pan-inner retinal transduction or significant outer retinal transduction beyond the fovea. Problems with retinal transduction by Ivt-delivered AAV include dilution in the vitreousMigratory 发表于 2025-3-22 17:12:25
http://reply.papertrans.cn/15/1449/144869/144869_7.pngexercise 发表于 2025-3-23 00:28:55
http://reply.papertrans.cn/15/1449/144869/144869_8.pngGEST 发表于 2025-3-23 05:15:07
http://reply.papertrans.cn/15/1449/144869/144869_9.pngRepetitions 发表于 2025-3-23 06:14:13
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