aspersion
发表于 2025-3-28 15:26:39
,Strategies for the Identification and Analysis of Viral Immune-Evasive Genes — Cytomegalovirus as atrol genomic maintenance and replication in specific tissues, others affect the immune control at various stages. Few immunomodulatory functions of genes can be predicted by sequence homology. The majority of genes with immunomodulatory properties only become apparent in functional assays. This chap
Ventricle
发表于 2025-3-28 20:24:48
Avoiding Proteasomal Processing: The Case of EBNA1,ssue development and atrophy, flux of substrates through metabolic pathways, selective elimination of abnormal proteins and processing of intracellular antigens for major histocompatibility complex (MHC) class I-restricted T-cell responses. Many viruses tamper with this proteolytic machinery by enco
肮脏
发表于 2025-3-29 01:42:51
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Extort
发表于 2025-3-29 06:32:46
Corking the Bottleneck: The Transporter Associated with Antigen Processing as a Target for Immune S which translocates cytosolic peptides into the endoplasmic reticulum (ER) for binding to MHC class I molecules. Although some DNA viruses, such as adenovirus or EBV, downmodulate TAP expression on the transcriptional level, members of the alpha and beta subfamily of herpesviruses, such as herpes si
incarcerate
发表于 2025-3-29 07:41:09
Herpes Viral Proteins Manipulating the Peptide Transporter TAP, peptides into the endoplasmic reticulum (ER) lumen for class I binding. It is therefore not surprising that TAP is targeted for inactivation by many viruses. Herpesviruses have been very successful in designing various proteins that inactivate TAP. We summarise current knowledge on the class I anti
Detoxification
发表于 2025-3-29 15:09:26
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忧伤
发表于 2025-3-29 15:43:54
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GRATE
发表于 2025-3-29 21:19:42
Viral Evasion of Natural Killer Cells During Human Cytomegalovirus Infection,o escape from this control. In particular, it down-regulates cell surface expression of HLA class I molecules. Because natural killer (NK) cells recognize and eliminate cells that lack HLA class I molecules. HCMV-infected cells could be more susceptible to NK lysis. In this review, we discuss the ro
Hla461
发表于 2025-3-30 02:52:28
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招募
发表于 2025-3-30 06:52:40
Human Cytomegalovirus Inhibition of Major Histocompatibility Complex Transcription and Interferon Sy effective at disabling key arms of the host immune response. For example, the herpesviruses establish a persistent infection in human and animal hosts, in part through critical immunoevasive strategies. Cytomegalovirus, a beta-herpesvirus, impairs major histocompatibility complex (MHC) class I and