丰满有漂亮
发表于 2025-3-25 05:22:58
V(D)J Recombination Deficiencies,strand breaks (dsb), whether they occur during V(D)J recombination or secondary to other DNA injuries. Two NHEJ factors, . and ., were indeed discovered through the study of human V(D)J recombination defective human SCID patients.
协奏曲
发表于 2025-3-25 10:29:21
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把手
发表于 2025-3-25 12:33:53
Regulation of V(D)J Recombination by E-Protein Transcription Factors,cells undergo recombination. E-proteins appear to be master regulators that coordinate antigen receptor gene rearrangement and expression. This chapter focuses on how E-proteins regulate V(D)J recombination by activating transcription, initiating rearrangement and driving differentiation during B- and T-cell development.
眨眼
发表于 2025-3-25 17:08:47
Temporal and Spatial Regulation of V(D)J Recombination: Interactions of Extrinsic Factors with the lex consisting of RAG-1 and RAG-2 subunits—and macromolecular assemblies extrinsic to the recombinase. This chapter will focus on those features of the recombinase itself—and in particular the RAG-2 subunit— that interact with extrinsic factors to establish patterns of temporal control and locus specificity in developing lymphocytes.
小步舞
发表于 2025-3-25 20:45:15
Daniel J. Bolland,Andrew L. Wood,Anne E. Corcoranamework used for the analysis of the companies. This section is followed by a discussion of the main results and the new communication and projection theory. The paper ends with a short discussion of implications for management.
Induction
发表于 2025-3-26 02:40:44
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宏伟
发表于 2025-3-26 08:23:02
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endarterectomy
发表于 2025-3-26 08:59:34
Regulation of RAG Transposition,es on the mechanism and regulation of RAG transposition. We first provide a brief overview of the biochemistry of V(D)J recombination. We then discuss the discovery of RAG transposition and present an overview of the RAG transposition pathway. Using this pathway as a framework, we discuss the factors and forces that regulate RAG transposition.
Irascible
发表于 2025-3-26 15:03:58
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eardrum
发表于 2025-3-26 20:36:45
Molecular Pathways and Mechanisms Regulating the Recombination of Immunoglobulin Genes during B-Lymcale chromatin dynamics and localized changes in chromatin structure in regulating the accessibility of Ig loci at specific stages of B-cell development. We review this emergent framework and discuss new experimental approaches that will be needed to explore the underlying molecular mechanisms.