CYN 发表于 2025-3-23 11:06:51
Urea Transporter Knockout Mice and Their Renal Phenotypes,ration in the inner medullary interstitium is not significantly affected by the absence of IMCD, descending limb of Henle and descending vasa recta urea transporters. Studies in urea transporter knockout mouse models have highlighted the essential role of urea for producing maximally concentrated urine.阴谋小团体 发表于 2025-3-23 14:21:14
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Overview and Historical Perspective,ogs, have two major subgroups, designated UT-B and UT-A. In kidney, UT-B is located primarily in the descending vasa recta. UT-A1 and UT-A3 are found in the inner medullary collecting duct, while UT-A2 is located in the thin descending limb. These transporters are crucial to the kidney’s ability to爱花花儿愤怒 发表于 2025-3-24 01:43:25
Urea,abolic process is altered in several conditions such as by diets, hormones, and diseases. Urea is then eliminated through fluids, especially urine. Blood urea nitrogen (BUN) has been utilized to evaluate renal function for decades. New roles for urea in the urinary system, circulation system, respirjungle 发表于 2025-3-24 06:22:55
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Genes and Proteins of Urea Transporters, contains two major subgroups: ., the UT-B urea transporter originally isolated from erythrocytes; and ., the UT-A group originally isolated from kidney inner medulla. ., the human UT-B gene, arises from a single locus located on chromosome 18q12.1-q21.1, which is located close to .. . includes 11 eBarter 发表于 2025-3-24 13:23:27
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Expression of Urea Transporters and Their Regulation,s chapter provides a brief overview of the expression of the urea transporter forms and their locations in the kidney. Rapid regulation of UT-A1 results from the combination of phosphorylation and membrane accumulation. Phosphorylation of UT-A1 has been linked to vasopressin and hyperosmolality, altarrogant 发表于 2025-3-24 21:46:50
http://reply.papertrans.cn/95/9442/944194/944194_19.pngAntecedent 发表于 2025-3-25 00:38:25
Transport Characteristics of Urea Transporter-B,dder, and testis. Expression of urea transporter UT-B confers high urea permeability to mammalian erythrocytes. Erythrocyte membranes are also permeable to various urea analogues, suggesting common transport pathways for urea and structurally similar solutes. UT-B is highly permeable to urea and the