Left-Atrium
发表于 2025-3-23 12:49:05
Uptake of Clostridial Neurotoxins into Cells and Dissemination, and undergoes a retrograde axonal transport to the spinal cord or brain, where the whole undissociated toxin is delivered and interacts with target neurons. Botulism most often results from ingestion of food contaminated with BoNT. Thus, BoNT passes through the intestinal epithelial barrier mainly
construct
发表于 2025-3-23 14:58:00
Receptors and Binding Structures for , Toxins A and B,entry into host cells by redundant endocytotic pathways. Although both homologous toxins do obviously not share the same receptors, this principle of redundant binding domains found for TcdB does also account for TcdA.
手段
发表于 2025-3-23 19:22:43
Cell Entry of C3 Exoenzyme from , ,cess to the intact cell. To date, no specific mechanism for internalization of C3 exoenzyme has been identified. Recently, vimentin was identified as membranous C3-binding partner involved in binding and uptake of C3. Although vimentin is not detected in neurons, vimentin is re-expressed after damag
chandel
发表于 2025-3-24 00:13:13
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石墨
发表于 2025-3-24 03:22:39
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Biomarker
发表于 2025-3-24 09:03:28
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Diluge
发表于 2025-3-24 12:19:49
Book 2017ng chapters focus on compounds which inhibit the transport of the A subunits from endosomes into the cytosol and therefore might lead to novel therapeutic strategies for toxin-associated diseases. These substances include pharmacological inhibitors of the host cell chaperones involved, as well as mu
commodity
发表于 2025-3-24 14:59:07
Andreas Rummelätzliche Koordinaten eingeführt werden. Linearisierte Kreiselgleichungen werden nach geeigneten Koordinatenumformungen mit Hilfe des Lagrange-Formalismus hergeleitet. Als Beispiel dient eine fliegend gelagerte Kreiselscheibe, für die freie und erzwungene Schwingungen reell und komplex berechnet und
Infiltrate
发表于 2025-3-24 22:32:08
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NUL
发表于 2025-3-25 02:54:34
Ralf Gerhardätzliche Koordinaten eingeführt werden. Linearisierte Kreiselgleichungen werden nach geeigneten Koordinatenumformungen mit Hilfe des Lagrange-Formalismus hergeleitet. Als Beispiel dient eine fliegend gelagerte Kreiselscheibe, für die freie und erzwungene Schwingungen reell und komplex berechnet und