嘲笑 发表于 2025-3-25 06:18:59
http://reply.papertrans.cn/95/9419/941882/941882_21.png小官 发表于 2025-3-25 07:49:09
Gert Janssenswillenody structure .. The question whether conformational changes are caused in the combining site has been of great concern in the context of understanding the mode of effector function activation mechanism.. Therefore, the effect induced in antibodies by binding their haptens or even larger parts of thPathogen 发表于 2025-3-25 13:03:50
http://reply.papertrans.cn/95/9419/941882/941882_23.pngobsession 发表于 2025-3-25 15:59:40
http://reply.papertrans.cn/95/9419/941882/941882_24.pngGROWL 发表于 2025-3-25 22:43:03
Gert Janssenswillendisease onset. Increasing evidence indicate that these autoantibodies play a role in the pathophysiology of RA and this is most likely related to the interaction with their target proteins, which are indeed present in the inflamed joints of RA patients. Although protein citrullination is not a uniqu显微镜 发表于 2025-3-26 01:17:34
http://reply.papertrans.cn/95/9419/941882/941882_26.pngMAPLE 发表于 2025-3-26 07:54:29
Gert Janssenswillennd minimal (<80 amino acids) structural motif. Artificial activities have been designed on these miniscaffolds by transferring previously identified protein active sites into regions structurally compatible with the site and permissive for sequence mutations. These newly designed miniproteins, preseHeresy 发表于 2025-3-26 09:25:12
http://reply.papertrans.cn/95/9419/941882/941882_28.png性行为放纵者 发表于 2025-3-26 15:20:52
Gert Janssenswillenns. Each technique has strengths and weaknesses and it is often useful to combine several approaches to maximize the former and minimize the latter. Here we review a range of methodologies that identify protein self-association and/or allow the stoichiometry and affinity of the interaction to be detenflame 发表于 2025-3-26 18:45:03
Gert Janssenswillen protein, with its specific three-dimensional structure, is stabilized relative to the unfolded (denatured) form, which is conformationally disperse. The related problems of protein dynamics, stability, and design are all related ultimately to protein energetics. Our knowledge of the . characteristi