UTTER 发表于 2025-3-25 06:34:37
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Mapping Molecular Datasets Back to the Brain Regions They are Extracted from: Remembering the Nativ the brain that they are derived from using digital atlas mapping techniques. We use, as an example, the transcriptomic, proteomic and peptidomic analyses conducted in the mammalian hypothalamus. Following a brief historical overview, we highlight studies that have mined biochemical and molecular ineulogize 发表于 2025-3-26 05:29:29
Genome-Scale Brain Metabolic Networks as Scaffolds for the Systems Biology of Neurodegenerative Dis-scale metabolic networks for such integration has led to the elucidation of cellular mechanisms for several cell types from microorganisms to plants. It has become easier and cheaper to generate high-throughput data over years in the form of transcriptome, proteome and metabolome. This has tremendocravat 发表于 2025-3-26 10:25:35
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Using Systems Biology and Mathematical Modeling Approaches in the Discovery of Therapeutic Targetsor biological process. Systems biology integrates genetics, signal transduction, biochemistry and cell biology with mathematical modeling. It can be used to identify novel pathways implicated in diseases as well as to understand the mechanisms by which a specific gene is regulated. This review desc