Lincoln
发表于 2025-3-21 17:14:14
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Brain-Imaging
发表于 2025-3-21 21:13:05
James Hughes57BL/6J (B6) inbred mice also demonstrate a significantly different ventilatory pattern during acute hypoxic challenge. The present study rejects the hypothesis that a genomic basis for differential hypoxic ventilatory responses (HVR) is linked to loci which determine differential breathing pattern
释放
发表于 2025-3-22 02:14:32
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Canopy
发表于 2025-3-22 08:11:26
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愤愤不平
发表于 2025-3-22 08:59:20
James Hughes57BL/6J (B6) inbred mice also demonstrate a significantly different ventilatory pattern during acute hypoxic challenge. The present study rejects the hypothesis that a genomic basis for differential hypoxic ventilatory responses (HVR) is linked to loci which determine differential breathing pattern
600
发表于 2025-3-22 16:13:41
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Demulcent
发表于 2025-3-22 18:11:13
James Hughes the body. The pathways over which peripheral chemoreccptor signals are transmitted to respiratory muscles arc well established. However, the intracellular pathways that transmit hypoxic stimulus to gene activation are just being identified. Using anti-sense c-fos strategy, we have shown that c-fos
萤火虫
发表于 2025-3-23 01:02:35
James Hughesonservative’ and ‘adaptable’ physiological characters involved in human responses to hypoxia. Conservative characters, arising by common descent, dominant and indeed define human physiology, but in five hypoxia response systems analyzed, we also found evidence for ‘adaptable’ characters at all level
桉树
发表于 2025-3-23 05:08:18
James Hughesn the cyclic AMP response element binding protein (CREB) transcription factor. PC 12 cells were exposed to moderate levels of hypoxia (5% O.) for various times between 20 min and 6 hr. We found that hypoxia rapidly and persistently induced ser. phosphorylation of CREB. This effect was more robust th
abject
发表于 2025-3-23 08:57:12
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