现存 发表于 2025-3-28 17:38:44
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dded systems. It provides an advanced parallel simulation infrastructure for efficient and effective system-level model validation and development so as to build better products in less time. Since parallel discrete event simulation (PDES) has the potential to exploit the underlying parallel compuExtemporize 发表于 2025-3-29 01:02:24
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Klaus von Beymeining the optimal designs of Phase 3 (Ph3) trials for a given budget. The model is formulated as a Stochastic Integer Programming (SIP) model that incorporates uncertainty regarding availability of drugs in the pipeline. The SIP model provides an . that specifies the optimal design for each drug for先行 发表于 2025-3-29 08:05:18
Martin Jänicke,Harald MönchPhase III testing according to predefined Go–No Go (GNG) criteria. The number of possible POC hypotheses likely far exceeds available public or private resources. In this chapter, we propose to find the optimal decisions by explicitly maximizing benefit–cost ratio (aka return on investment), which i盖他为秘密 发表于 2025-3-29 14:29:21
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978-3-531-12014-0Springer Fachmedien Wiesbaden 1988sphincter 发表于 2025-3-30 01:36:51
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